Article
Inference on the Genetic Basis of Eye and Skin Color in an Admixed Population via Bayesian Linear Mixed Models.
Genetics - 1 Jun 2017
Lloyd-Jones Luke R, Robinson Matthew R, Moser Gerhard, Zeng Jian, Beleza Sandra, Barsh Gregory S, Tang Hua, Visscher Peter M
Abstract excerpt
Genetic association studies in admixed populations are underrepresented in the genomics literature, with a key concern for researchers being the adequate control of spurious associations due to population structure. Linear mixed models (LMMs) are well suited for genome-wide association studies (GWAS) because they account for both population stratification and cryptic relatedness and achieve increased statistical...
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