Article
Single nucleotide polymorphisms in the bovine MHC region of Japanese Black cattle are associated with bovine leukemia virus proviral load.
Retrovirology - 4 Apr 2017
Takeshima Shin-Nosuke, Sasaki Shinji, Meripet Polat, Sugimoto Yoshikazu, Aida Yoko
Abstract excerpt
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, a malignant B cell lymphoma that has spread worldwide and causes serious problems for the cattle industry. The BLV proviral load, which represents the BLV genome integrated into host genome, is a useful index for estimating disease progression and transmission risk. Here, we conducted a genome-wide association study to identify single...
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