Article
Prevalence and genetic variants of G6PD deficiency among two Malagasy populations living in Plasmodium vivax-endemic areas.
Malaria journal - 4 Apr 2017
Howes Rosalind E, Chan Ernest R, Rakotomanga Tovonahary Angelo, Schulte Seth, Gibson John, Zikursh Melinda, Franchard Thierry, Ramiranirina Brune, Ratsimbasoa Arsène, Zimmerman Peter A
Abstract excerpt
BACKGROUND: The prevalence and variants of G6PD deficiency in the Plasmodium vivax-endemic zones of Madagascar remain unknown. The admixed African-Austronesian origins of the Malagasy population make it probable that a heterogeneous mix of genetic variants with a spectrum of clinical severity will be circulating. This would have implications for the widespread use of P. vivax radical cure therapy. Two study...
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