Article
Human papillomavirus 16 is an aetiological factor of scrotal cancer.
British journal of cancer - 25 Apr 2017
Guimerà Núria, Alemany Laia, Halec Gordana, Pawlita Michael, Wain Gerard Vincent, Vailén José Santos Salas, Azike Jerome E, Jenkins David, de Sanjosé Silvia, Quint Wim, Bosch F Xavier
Abstract excerpt
BACKGROUND: Squamous cell scrotal carcinoma (SCSC) is an infrequent skin cancer associated historically with occupational carcinogens. Human papillomavirus (HPV) DNA has been associated with SCSC but there is no definitive proof of its oncogenic role. METHODS: Human papillomavirus-DNA and -E6*I mRNA were analysed in six invasive histologically typed SCSC. LCM-PCR was used to localise HPV DNA to tumour cells....
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