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Article

Cell-free DNA as biomarker and source for mutation detection in primary colorectal cancer.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Nikolic Aleksandra, Vlajnic Marina, Ristanovic Momcilo, Petrovic Jelena, Dimitrijevic Ivan, Krivokapic Zoran, Radojkovic Dragica

Abstract excerpt

PURPOSE: To analyze if cell-free (cf)DNA levels and the presence of KRAS and BRAF mutations in serum could be used as diagnostic biomarkers in patients with primary colorectal cancer (CRC). METHODS: This study included 92 individuals who were operated due to primary CRC (N=52;study group) and to hemorrhoids (N=40;control group). Serum cfDNA levels were measured with real-time PCR (RT-PCR) using PicoGreen dsDNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28365952

Genes

KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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