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Article

Cell-free DNA in healthy individuals, noncancerous disease and strong prognostic value in colorectal cancer.

International journal of cancer - 15 Dec 2014

Spindler Karen-Lise Garm, Appelt Ane L, Pallisgaard Niels, Andersen Rikke F, Brandslund Ivan, Jakobsen Anders

Abstract excerpt

The purpose was to investigate total cell-free DNA (cfDNA) in colorectal cancer (CRC) patients during treatment with second-line chemotherapy and in healthy controls and patients with different comorbidities. Patient treated with second-line irinotecan for metastatic CRC (n = 100), a cohort of healthy controls with and without comorbidity (n = 70 and 100, respectively) were included. cfDNA was quantified by an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24798213
DOI: 10.1002/ijc.28946

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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