Article
A possible role for CD26/DPPIV enzyme activity in the regulation of psoriatic pruritus.
Journal of dermatological science - 1 Jun 2017
Komiya Eriko, Hatano Ryo, Otsuka Haruna, Itoh Takumi, Yamazaki Hiroto, Yamada Taketo, Dang Nam H, Tominaga Mitsutoshi, Suga Yasushi, Kimura Utako, Takamori Kenji, Morimoto Chikao, Ohnuma Kei
Abstract excerpt
BACKGROUND: Psoriasis (PSO) is one of the most common chronic inflammatory skin diseases, and pruritus affects approximately 60-90% of patients with PSO. However, the pathogenesis of pruritus in PSO remains unclear. Dipeptidyl peptidase IV (DPPIV) enzyme activity is involved in the regulation of peptide hormones, chemokines and neurotransmitters. OBJECTIVES: Our aim is to evaluate for a potential association...
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