Article
Lack of association between the IL-10 gene polymorphisms and features of the metabolic syndrome.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Feb 2011
Lu Ming-Ying, Lakkakula Bhaskar V K S, Liao Yi-Chu, Tsai Pei-Chien, Yang Yi-Hsin, Juo Suh-Hang Hank
Abstract excerpt
BACKGROUNDS: Insulin resistance plays a major role in the pathogenesis of the metabolic syndrome. Inflammation is the leading cause of insulin resistance, and interleukin 10 (IL-10) is one of the anti-inflammatory cytokines. We conducted a case-control study to investigate the association between the IL-10 polymorphisms and the metabolic syndrome. METHODS: One thousand two hundred two unrelated subjects residing...
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