Article
Whole-Genome Sequencing of Measles Virus Genotypes H1 and D8 During Outbreaks of Infection Following the 2010 Olympic Winter Games Reveals Viral Transmission Routes.
The Journal of infectious diseases - 15 Nov 2015
Gardy Jennifer L, Naus Monika, Amlani Ashraf, Chung Walter, Kim Hochan, Tan Malcolm, Severini Alberto, Krajden Mel, Puddicombe David, Sahni Vanita, Hayden Althea S, Gustafson Reka, Henry Bonnie, Tang Patrick
Abstract excerpt
We used whole-genome sequencing to investigate a dual-genotype outbreak of measles occurring after the XXI Olympic Winter Games in Vancouver, Canada. By sequencing 27 complete genomes from H1 and D8 genotype measles viruses isolated from outbreak cases, we estimated the virus mutation rate, determined that person-to-person transmission is typically associated with 0 mutations between isolates, and established...
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