Article
Epidemiology and Molecular Basis of Resistance to Fluconazole Among Clinical Candida parapsilosis Isolates in Kuwait.
Microbial drug resistance (Larchmont, N.Y.) - 1 Dec 2017
Asadzadeh Mohammad, Ahmad Suhail, Al-Sweih Noura, Khan Ziauddin
Abstract excerpt
Fluconazole resistance among clinical Candida parapsilosis isolates is an emerging problem in many countries, including Kuwait. Resistance to fluconazole is mediated by amino acid substitutions in ERG11 and/or by overexpression of efflux pumps MDR1 and CDR1. Clinical C. parapsilosis sensu stricto isolates (n = 442) were tested for susceptibility to fluconazole by Etest, Vitek II, and broth microdilution methods....
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