Article
Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.
BMC neurology - 25 Sept 2013
Gao Kai, Deng Xiong, Zheng Wen, Song Zhi, Zhu Anding, Xiu Xiaofei, Deng Hao
Abstract excerpt
BACKGROUND: Parkinson's disease (PD), the second most common neurodegenerative disease, is characterized by loss of dopaminergic neurons in the substantia nigra. The clinical manifestations of PD encompass a variety of motor and non-motor symptoms. Mutations in the F-box protein 7 gene (FBXO7) have been identified to cause Parkinsonian-pyramidal syndrome, an autosomal recessive form of Parkinsonism. The F-box...
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