Article
Activation of Myeloid TLR4 Mediates T Lymphocyte Polarization after Traumatic Brain Injury.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 2017
Braun Molly, Vaibhav Kumar, Saad Nancy, Fatima Sumbul, Brann Darrell W, Vender John R, Wang Lei P, Hoda Md Nasrul, Baban Babak, Dhandapani Krishnan M
Abstract excerpt
Traumatic brain injury (TBI) is a major public health issue, producing significant patient mortality and poor long-term outcomes. Increasing evidence suggests an important, yet poorly defined, role for the immune system in the development of secondary neurologic injury over the days and weeks following a TBI. In this study, we tested the hypothesis that peripheral macrophage infiltration initiates long-lasting...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.