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From rabbit antibody repertoires to rabbit monoclonal antibodies

24 Mar 2017

Abstract excerpt

In this review, we explain why and how rabbit monoclonal antibodies have become outstanding reagents for laboratory research and increasingly for diagnostic and therapeutic applications. Starting with the unique ontogeny of rabbit B cells that affords highly distinctive antibody repertoires rich in in vivo pruned binders of high diversity, affinity and specificity, we describe the generation of rabbit monoclonal...

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PMID: 28336958
DOI: 10.1038/emm.2017.23

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