Article
Testis-specific ATP synthase peripheral stalk subunits required for tissue-specific mitochondrial morphogenesis in Drosophila.
BMC cell biology - 23 Mar 2017
Sawyer Eric M, Brunner Elizabeth C, Hwang Yihharn, Ivey Lauren E, Brown Olivia, Bannon Megan, Akrobetu Dennis, Sheaffer Kelsey E, Morgan Oshauna, Field Conroy O, Suresh Nishita, Gordon M Grace, Gunnell E Taylor, Regruto Lindsay A, Wood Cricket G, Fuller Margaret T, Hales Karen G
Abstract excerpt
BACKGROUND: In Drosophila early post-meiotic spermatids, mitochondria undergo dramatic shaping into the Nebenkern, a spherical body with complex internal structure that contains two interwrapped giant mitochondrial derivatives. The purpose of this study was to elucidate genetic and molecular mechanisms underlying the shaping of this structure. RESULTS: The knotted onions (knon) gene encodes an unconventionally...
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