Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Improved lysis efficiency and immunogenicity of Salmonella ghosts mediated by co-expression of λ phage holin-endolysin and ɸX174 gene E

23 Mar 2017

Abstract excerpt

Bacterial ghosts (BGs) are empty cell envelopes derived from Gram-negative bacteria by bacteriophage ɸX174 gene E mediated lysis. They represent a novel inactivated vaccine platform; however, the practical application of BGs for human vaccines seems to be limited due to the safety concerns on the presence of viable cells in BGs. Therefore, to improve the lysis efficiency of the gene E, we exploited the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aquaculture disease management and microbiota
Share to Bacteriophages and microbial interactions
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28332591
DOI: 10.1038/srep45139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Improved lysis efficiency and immunogenicity of Salmonella ghosts mediated by co-expression of λ phage holin-endolysin and ɸX174 gene EPMID 28332591Read ↗

A Novel and Efficient High-Yield Method for Preparing Bacterial Ghosts.Semantic proximity Read ↗

Efficient Robust Yield Method for Preparing Bacterial Ghosts by Escherichia coli Phage ID52 Lysis Protein ESemantic proximity Read ↗

Salmonella Typhimurium, the major causative agent of foodborne illness inactivated by a phage lysis system provides effective protection against lethal challenge by induction of robust cell-mediated immune responses and activation of dendritic cellsSemantic proximity Read ↗

Yersinia enterocolitica ghost with msbB mutation provides protection and reduces proinflammatory cytokines in mice.Semantic proximity Read ↗

Production and Characterization of Bacterial Ghost Vaccine against Neisseria meningitidisSemantic proximity Read ↗

Characterization of Streptococcus iniae ghost vaccine and its immunization in Nile tilapia (Oreochromis niloticus)Semantic proximity Read ↗

Construction of Vibrio mimicus ghosts as a novel inactivated vaccine candidate and its protective efficacy against ascites disease in grass carps (Ctenopharyngodon idella)Semantic proximity Read ↗

Engineered Endolysin-based "Artilysins" for Controlling the Gram-negative Pathogen Helicobacter PyloriSemantic proximity Read ↗

Oncolysate-loaded Escherichia coli bacterial ghosts enhance the stimulatory capacity of human dendritic cells.Semantic proximity Read ↗

Generation and use of Edwardsiella ictaluri ghosts as a vaccine against enteric septicemia of catfish (ESC)Semantic proximity Read ↗

Detoxified pneumolysin derivative Plym2 directly protects against pneumococcal infection via induction of inflammatory cytokines.Semantic proximity Read ↗

Elucidating Physicochemical Features of Holin Proteins Responsible for Bacterial Cell Lysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.