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Article

Production and Characterization of Bacterial Ghost Vaccine against Neisseria meningitidis

23 Dec 2022

Abstract excerpt

Bacterial ghosts (BGS) are empty non-living envelopes produced either genetically or chemically. This study investigated a novel chemical protocol for the production of Neisseria meningitidis ghost vaccine using tween 80 followed by a pH reduction with lactic acid. For our vaccine candidate, both safety and immunogenicity aspects were evaluated. The ghost pellets showed no sign of growth upon cultivation. BGS...

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Identifiers

PMID: 36679882
DOI: 10.3390/vaccines11010037

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