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Metabolic re-wiring of isogenic breast epithelial cell lines following epithelial to mesenchymal transition

18 Mar 2017

Abstract excerpt

Epithelial to mesenchymal transition (EMT) has implications in tumor progression and metastasis. Metabolic alterations have been described in cancer development but studies focused on the metabolic re-wiring that takes place during EMT are still limited. We performed metabolomics profiling of a breast epithelial cell line and its EMT derived mesenchymal phenotype to create genome-scale metabolic models...

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PMID: 28323032
DOI: 10.1016/j.canlet.2017.03.019

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