Article
Analysis of a Novel Multiplex Polymerase Chain Reaction Assay as a Sensitive Tool for the Diagnosis of Indeterminate and Tuberculoid Forms of Leprosy
1 Jan 2017
Abstract excerpt
OBJECTIVE/BACKGROUND: Clinical diagnosis of indeterminate and tuberculoid leprosy is often difficult due to limited and confounding signs and symptoms. In the current study, we evaluated the utility of new multiplex polymerase chain reaction (PCR) using Mycobacterium leprae-specific DNA sequences in the pseudogene regions of ML1545, ML2180, and ML2179 for PCR-based diagnosis of indeterminate leprosy (IND) and...
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