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Article

Evaluation of qPCR-Based Assays for Leprosy Diagnosis Directly in Clinical Specimens

11 Oct 2011

Abstract excerpt

The increased reliability and efficiency of the quantitative polymerase chain reaction (qPCR) makes it a promising tool for performing large-scale screening for infectious disease among high-risk individuals. To date, no study has evaluated the specificity and sensitivity of different qPCR assays for leprosy diagnosis using a range of clinical samples that could bias molecular results such as...

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PMID: 22022631
DOI: 10.1371/journal.pntd.0001354

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