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Article

Multi-omics Profiling of Patients with Melanoma Treated with Nivolumab in Project HOPE.

Anticancer research - 1 Mar 2017

Yoshikawa Shusuke, Kiyohara Yoshio, Otsuka Masaki, Kondou Ryota, Nonomura Chizu, Miyata Haruo, Iizuka Akira, Ohshima Keiichi, Urakami Kenichi, Nagashima Takeshi, Kusuhara Masatoshi, Sugino Takashi, Mochizuki Tohru, Yamaguchi Ken, Akiyama Yasuto

Abstract excerpt

BACKGROUND: Project HOPE (High-tech Omics-based Patient Evaluation) has been in progress since 2014 and uses whole-exome sequencing (WES) and gene expression profiling (GEP). Among a total of 1,685 patients with cancer, 13 with melanoma were registered and characterized using multi-omics analyses to investigate specific biomarkers in responders to programmed cell death-1 (PD-1) blockade. MATERIALS AND METHODS:...

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Identifiers

PMID: 28314298
DOI: 10.21873/anticanres.11450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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