Article
Identification of Methylation Profiles of Cancer-related Genes in Circulating Tumor Cells Population.
Anticancer research - 1 Mar 2017
Lyberopoulou Anna, Galanopoulos Michail, Aravantinos Gerasimos, Theodoropoulos George E, Marinos Evangelos, Efstathopoulos Efstathios P, Gazouli Maria
Abstract excerpt
BACKGROUND: We performed an epigenetic analysis of the first exon of the hVIM gene and the SFRP2 in circulating tumor cells (CTCs) and correlation with the corresponding primary colorectal cancer (CRC) tissue. PATIENTS AND METHODS: CTCs detection in 52 colorectal cancer patients was managed by a multi-marker immunomagnetic method with the use of quantum dots (QDs). To determine methylation levels we used...
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