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Article

Matrix Metalloproteases as Biomarkers of Disease.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Fonseca Fernando Luiz Affonso, da Costa Aguiar Alves Beatriz, Azzalis Ligia Ajaime, Belardo Thaís Moura Gáscon

Abstract excerpt

Matrix metalloprotease play a vital role in many cellular processes. Dysfunction in activity of these enzymes has been implicated in the pathogenesis of a number of diseases. Factors that affect the balanced interaction between MMPs and their inhibitors, such as genetic mutations of extracellular matrix components or dysregulation of MMP expression, can lead to various diseases. Due to their essential role in ECM...

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PMID: 28299745
DOI: 10.1007/978-1-4939-6863-3_17

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