Article
The changing picture of amyotrophic lateral sclerosis: lessons from European registers.
Journal of neurology, neurosurgery, and psychiatry - 1 Jul 2017
Hardiman Orla, Al-Chalabi Ammar, Brayne Carol, Beghi Ettore, van den Berg Leonard H, Chio Adriano, Martin Sarah, Logroscino Giancarlo, Rooney James
Abstract excerpt
Prospective population based-registers of amyotrophic lateral sclerosis (ALS) have operated in Europe for over two decades, and have provided important insights into our understanding of ALS. Here, we review the benefits that population registers have brought to the understanding of the incidence, prevalence, phenotype and genetics of ALS and outline the core operating principles that underlie these registers and...
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