Article
Zinc stress induces copper depletion in Acinetobacter baumannii.
BMC microbiology - 11 Mar 2017
Hassan Karl A, Pederick Victoria G, Elbourne Liam D H, Paulsen Ian T, Paton James C, McDevitt Christopher A, Eijkelkamp Bart A
Abstract excerpt
BACKGROUND: The first row transition metal ions zinc and copper are essential to the survival of many organisms, although in excess these ions are associated with significant toxicity. Here, we examined the impact of zinc and copper stress on Acinetobacter baumannii, a common opportunistic pathogen. RESULTS: We show that extracellular zinc stress induces a copper-specific depletion phenotype in A. baumannii ATCC...
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