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Article

Reduced H3K27me3 expression in Merkel cell polyoma virus-positive tumors.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2017

Busam Klaus J, Pulitzer Melissa P, Coit Daniel C, Arcila Maria, Leng Danielle, Jungbluth Achim A, Wiesner Thomas

Abstract excerpt

Merkel cell carcinoma is a primary cutaneous neuroendocrine carcinoma, which once metastatic is difficult to treat. Recent mutation analyses of Merkel cell carcinoma revealed a low number of mutations in Merkel cell polyomavirus-associated tumors, and a high number of mutations in virus-negative combined squamous cell and neuroendocrine carcinomas of chronically sun-damaged skin. We speculated that the paucity of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28281550
DOI: 10.1038/modpathol.2017.8
PMCID: PMC5451312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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