Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estrogen receptors in granulosa cells govern meiotic resumption of pre-ovulatory oocytes in mammals

9 Mar 2017

Abstract excerpt

In mammals, oocytes are arrested at the diplotene stage of meiosis I until the pre-ovulatory luteinizing hormone (LH) surge triggers meiotic resumption through the signals in follicular granulosa cells. In this study, we show that the estradiol (E2)-estrogen receptors (ERs) system in follicular granulosa cells has a dominant role in controlling oocyte meiotic resumption in mammals. We found that the expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28277543
DOI: 10.1038/cddis.2017.82

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estrogen receptors in granulosa cells govern meiotic resumption of pre-ovulatory oocytes in mammalsPMID 28277543Read ↗

Estradiol Signaling at the Heart of Folliculogenesis: Its Potential Deregulation in Human Ovarian PathologiesSemantic proximity Read ↗

The art of oocyte meiotic arrest regulationSemantic proximity Read ↗

CNP/NPR2 signaling maintains oocyte meiotic arrest in early antral follicles and is suppressed by EGFR‐mediated signaling in preovulatory folliclesSemantic proximity Read ↗

The molecular regulatory mechanisms of meiotic arrest and resumption in Oocyte development and maturationSemantic proximity Read ↗

ESR2 regulates granulosa cell genes essential for follicle maturation and ovulation.Semantic proximity Read ↗

Mechanisms of Oocyte Maturation and Related Epigenetic RegulationSemantic proximity Read ↗

Oocyte Maturation A story of arrest and releaseSemantic proximity Read ↗

Towards a new understanding on the regulation of mammalian oocyte meiosis resumptionSemantic proximity Read ↗

Significance of epidermal growth factor receptor signaling for acquisition of meiotic and developmental competence in mammalian oocytes†Semantic proximity Read ↗

Stops and starts in mammalian oocytes: recent advances in understanding the regulation of meiotic arrest and oocyte maturationSemantic proximity Read ↗

Luteinizing Hormone Action in Human Oocyte Maturation and Quality: Signaling Pathways, Regulation, and Clinical ImpactSemantic proximity Read ↗

Selective Regulation of Oocyte Meiotic Events Enhances Progress in Fertility Preservation MethodsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.