Article
Mutational Pressure in Zika Virus: Local ADAR-Editing Areas Associated with Pauses in Translation and Replication.
Frontiers in cellular and infection microbiology - 1 Jan 2017
Khrustalev Vladislav V, Khrustaleva Tatyana A, Sharma Nitin, Giri Rajanish
Abstract excerpt
Zika virus (ZIKV) spread led to the recent medical health emergency of international concern. Understanding the variations in virus system is of utmost need. Using available complete sequences of ZIKV we estimated directions of mutational pressure along the length of consensus sequences of three lineages of the virus. Results showed that guanine usage is growing in ZIKV RNA plus strand due to adenine to guanine...
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