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Article

miR-124 targets GATA6 to suppress cholangiocarcinoma cell invasion and metastasis

7 Mar 2017

Abstract excerpt

BACKGROUND: Our previous study showed that GATA6 plays important roles in cholangiocarcinoma (CCA) cell invasion and metastasis. However, the regulation mechanism of GATA6 in CCA is not clear. In this study, we studied the potential function of miR-124 in CCA and the mechanism of GATA6 regulation. METHODS: The expression levels of miR-124 and GATA6 in cancerous tissues from 57 CCA patients was detected by RT-PCR...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 28270130
DOI: 10.1186/s12885-017-3166-z

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