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Article

The Influence of Methotrexate Treatment on Male Fertility and Pregnancy Outcome After Paternal Exposure

7 Mar 2017

Abstract excerpt

BACKGROUND: Inflammatory bowel disease incidence peaks during the reproductive years. Methotrexate (MTX) is frequently used for inflammatory bowel disease, but its use during pregnancy is contraindicated in women because of teratogenic effects. The aim of this review is to investigate the influence of MTX on male fertility and pregnancy outcomes after paternal MTX exposure. METHODS: A systematic literature search...

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PMID: 28267049
DOI: 10.1097/mib.0000000000001064

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