Article
A case of methotrexate embryopathy with holoprosencephaly, expanding the phenotype.
Birth defects research. Part A, Clinical and molecular teratology - 1 Feb 2006
Seidahmed Mohammed Zain, Shaheed Meeralebbae M, Abdulbasit Omar B, Al Dohami Hessa, Babiker Mirghani, Abdullah Mohammed A, Abomelha Abdullah M
Abstract excerpt
BACKGROUND: Methotrexate (MTX) embryopathy was described nearly 50 years ago, when this agent began to be used as a cancer treatment and abortifacient. In this report we describe a case with typical features of MTX syndrome together with new features to expand the phenotype. CASE: A 29-year-old woman decided to terminate her unwanted pregnancy because of ill health, as she had conceived soon after her last...
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