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Article

Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Aug 2017

Capozzo Rosa, Sassi Celeste, Hammer Monia B, Arcuti Simona, Zecca Chiara, Barulli Maria R, Tortelli Rosanna, Gibbs J Raphael, Crews Cynthia, Seripa Davide, Carnicella Francesco, Dell'Aquila Claudia, Rossi Marco, Tamma Filippo, Valluzzi Francesco, Brancasi Bruno, Panza Francesco, Singleton Andrew B, Logroscino Giancarlo

Abstract excerpt

INTRODUCTION: We investigated the clinical differences between familial and sporadic frontotemporal dementia (FTD), screening for mutations in known FTD genes. METHODS: We diagnosed 22 affected individuals belonging to eight families and 43 sporadic cases with FTD in Apulia, Southern Italy, in 2 years. Mutations in common causative FTD genes (GRN, MAPT, VCP, and TARDBP) and C9ORF72 expansions were screened....

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Identifiers

PMID: 28264768
DOI: 10.1016/j.jalz.2017.01.011
PMCID: PMC6232845

Genes

GRN
MAPT
TARDBP
VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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