Article
MicroRNA-150 Modulates Ischemia-Induced Neovascularization in Atherosclerotic Conditions.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 2017
Desjarlais Michel, Dussault Sylvie, Dhahri Wahiba, Mathieu Raphael, Rivard Alain
Abstract excerpt
OBJECTIVE: Hypercholesterolemia is an atherosclerotic condition that is associated with impaired neovascularization in response to ischemia. This study sought to define the role of microRNAs in that pathophysiology. APPROACH AND RESULTS: Next-generation sequencing and quantitative reverse transcription polymerase chain reaction analyses identified miR-150 as a proangiogenic microRNA, which expression is...
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