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Article

MicroRNA-185 induces potent autophagy via AKT signaling in hepatocellular carcinoma

1 Feb 2017

Abstract excerpt

Studies have demonstrated that microRNA 185 may be a promising therapeutic target in liver cancer. However, its role in hepatocellular carcinoma is largely unknown. In this study, the proliferation of human HepG2 cells was inhibited by transfection of microRNA 185 mimics. Cell-cycle analysis revealed arrest at the G0/G1 phase. Transfection of HepG2 cells with microRNA 185 mimics significantly induced apoptosis....

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Share to Autophagy in Disease and Therapy
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PMID: 28240051
DOI: 10.1177/1010428317694313

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