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Article

A novel anti-lipopolysaccharide factor SpALF6 in mud crab Scylla paramamosain exhibiting different antimicrobial activity from its single amino acid mutant.

Developmental and comparative immunology - 1 Jul 2017

Hou Zhi-Guo, Wang Yuan, Hui Kaimin, Fang Wen-Hong, Zhao Shu, Zhang Jing-Xiao, Ma Hongyu, Li Xin-Cang

Abstract excerpt

In crustaceans, anti-lipopolysaccharide factors (ALFs) are important immune effectors that have sequence diversity and exhibit broad antimicrobial activities. In this study, we characterized a novel ALF homolog SpALF6 from mud crab Scylla paramamosain and its variant SpALF6-V, which was generated by mutations of two amino acids (H46 to R and A110 to P) due to the presence of two single nucleotide polymorphisms...

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PMID: 28232132
DOI: 10.1016/j.dci.2017.02.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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