Article
Functional divergence in shrimp anti-lipopolysaccharide factors (ALFs): from recognition of cell wall components to antimicrobial activity.
PloS one - 1 Jan 2013
Rosa Rafael Diego, Vergnes Agnès, de Lorgeril Julien, Goncalves Priscila, Perazzolo Luciane Maria, Sauné Laure, Romestand Bernard, Fievet Julie, Gueguen Yannick, Bachère Evelyne, Destoumieux-Garzón Delphine
Abstract excerpt
Antilipopolysaccharide factors (ALFs) have been described as highly cationic polypeptides with a broad spectrum of potent antimicrobial activities. In addition, ALFs have been shown to recognize LPS, a major component of the Gram-negative bacteria cell wall, through conserved amino acid residues exposed in the four-stranded β-sheet of their three dimensional structure. In penaeid shrimp, ALFs form a diverse...
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