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Cloning and characterisation of the SpToll gene from green mud crab, Scylla paramamosain.

Developmental and comparative immunology - 1 May 2012

Lin Zhongyang, Qiao Jie, Zhang Yueling, Guo Lingling, Huang He, Yan Fang, Li Yuanyou, Wang Xiuying

Abstract excerpt

Toll/Toll-like receptors (TLRs), one of the most important pattern recognition receptors (PRRs), play a crucial role in innate immune responses in both invertebrates and vertebrates. In this study, we cloned and characterised a Toll gene from Scylla paramamosain (SpToll). Bioinformatic analysis predicted that SpToll contained one open reading frame of 3018bp and encoded a single-pass transmembrane domain protein...

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PMID: 21945833
DOI: 10.1016/j.dci.2011.09.003

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