Article
Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.
International archives of allergy and immunology - 1 Jan 2017
Trzeciak Magdalena, Sakowicz-Burkiewicz Monika, Wesserling Martyna, Gleń Jolanta, Dobaczewska Daria, Bandurski Tomasz, Nowicki Roman, Pawelczyk Tadeusz
Abstract excerpt
BACKGROUND: It is assumed that beside alterations in the filaggrin gene (FLG), disturbances within genes encoding other cornified envelope proteins are also involved in atopic dermatitis (AD). To identify new potential markers of AD, we studied the polymorphisms of genes encoding repetin (RPTN), cornulin (CRNN), and their expression in the skin of AD patients. METHODS: Polymorphisms in CRNN (rs941934), RPTN...
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