Article
Development of an anti-ferret CD4 monoclonal antibody for the characterisation of ferret T lymphocytes.
Journal of immunological methods - 1 May 2017
Layton Daniel S, Xiao Xiaowen, Bentley John D, Lu Louis, Stewart Cameron R, Bean Andrew G D, Adams Timothy E
Abstract excerpt
The ferret is an established animal model for a number of human respiratory viral infections, such as influenza virus and more recently, Ebola virus. However, a paucity of immunological reagents has hampered the study of cellular immune responses. Here we describe the development and characterisation of a novel monoclonal antibody (mAb) against the ferret CD4 antigen and the characterisation of ferret CD4 T...
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