Article
Individualized corrected QT interval is superior to QT interval corrected using the Bazett formula in predicting mutation carriage in families with long QT syndrome.
Heart rhythm - 1 Mar 2017
Robyns Tomas, Willems Rik, Vandenberk Bert, Ector Joris, Garweg Christophe, Kuiperi Cuno, Breckpot Jeroen, Corveleyn Anniek, Janssens Stefan, Heidbuchel Hein, Nuyens Dieter
Abstract excerpt
BACKGROUND: Long QT syndrome (LQTS) is characterized by reduced penetrance and variable QT prolongation over time, resulting in an estimate of 25% carriers of a pathogenic mutation with a normal corrected QT (QTc) interval on the resting electrocardiogram (ECG). OBJECTIVE: The purpose of this study was to test the hypothesis that an individualized corrected QT interval derived from 24-hour Holter data more...
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