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Article

Developmental Programming of Adult Disease: Reprogramming by Melatonin?

16 Feb 2017

Abstract excerpt

Adult-onset chronic non-communicable diseases (NCDs) can originate from early life through so-called the "developmental origins of health and disease" (DOHaD) or "developmental programming". The DOHaD concept offers the "reprogramming" strategy to shift the treatment from adulthood to early life, before clinical disease is apparent. Melatonin, an endogenous indoleamine produced by the pineal gland, has...

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PMID: 28212315
DOI: 10.3390/ijms18020426

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