Article
Deciphering the distance to antibiotic resistance for the pneumococcus using genome sequencing data.
Scientific reports - 16 Feb 2017
Mobegi Fredrick M, Cremers Amelieke J H, de Jonge Marien I, Bentley Stephen D, van Hijum Sacha A F T, Zomer Aldert
Abstract excerpt
Advances in genome sequencing technologies and genome-wide association studies (GWAS) have provided unprecedented insights into the molecular basis of microbial phenotypes and enabled the identification of the underlying genetic variants in real populations. However, utilization of genome sequencing in clinical phenotyping of bacteria is challenging due to the lack of reliable and accurate approaches. Here, we...
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