Article
A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro.
Scientific reports - 15 Feb 2017
Wang Deping, Chen Cheng, Liu Shengnan, Zhou Han, Yang Kailin, Zhao Qi, Ji Xiaoyun, Chen Chen, Xie Wei, Wang Zefang, Mi Li-Zhi, Yang Haitao
Abstract excerpt
An unprecedented epidemic of Zika virus (ZIKV) infection had spread to South and Central America. ZIKV infection was recently confirmed by CDC (the Centers for Disease Control and Prevention) to cause neonatal microcephaly, which posed a significant public health emergency of international concern. No specific vaccines or drugs are currently available to fight ZIKV infection. ZIKV nonstructural protein 1 (NS1)...
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