Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oculomotor deficits in spinocerebellar ataxia type 3: Potential biomarkers of preclinical detection and disease progression.

CNS neuroscience & therapeutics - 1 Apr 2017

Wu Chao, Chen Ding-Bang, Feng Li, Zhou Xiang-Xue, Zhang Ji-Wei, You Hua-Jing, Liang Xiu-Ling, Pei Zhong, Li Xun-Hua

Abstract excerpt

AIMS: To detect specific oculomotor deficits in preclinical stage of spinocerebellar ataxia type 3 (SCA3) and evaluate whether these abnormalities prove useful as potential biomarkers of disease progression. METHODS: A Chinese cohort of 56 patients with SCA3, including 12 preclinical carriers of SCA3 (pre-SCA3) and 44 manifest SCA3, and 26 healthy control individuals were recruited. We performed a detailed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxin-3
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Machado-Joseph Disease

Share to Mental Status Schedule

Share to Ocular Motility Disorders

Share to Repressor Proteins

Share to Severity of Illness Index

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28195427
DOI: 10.1111/cns.12676
PMCID: PMC6492748

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oculomotor deficits in spinocerebellar ataxia type 3: Potential biomarkers of preclinical detection and disease progression.PMID 28195427Read ↗

Oculomotor phenotypes in autosomal dominant ataxias.Semantic proximity Read ↗

Quantitative Oculomotor Assessment in Hereditary Ataxia: Discriminatory Power, Correlation with Severity Measures, and Recommended Parameters for Specific Genotypes.Semantic proximity Read ↗

Ocular Motor and Vestibular Profile in Spinocerebellar Ataxia Type 27B: Toward a Practical Bedside Diagnostic FrameworkSemantic proximity Read ↗

Eye movement abnormalities in spinocerebellar ataxia type 17 (SCA17).Semantic proximity Read ↗

The influence of initial symptoms on phenotypes in spinocerebellar ataxia type 3Semantic proximity Read ↗

Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3.Semantic proximity Read ↗

The Association Between Diplopia and Clinical Phenotypes in Spinocerebellar Ataxia Type 3Semantic proximity Read ↗

Comprehensive study of early features in spinocerebellar ataxia 2: delineating the prodromal stage of the disease.Semantic proximity Read ↗

Eye movement abnormalities correlate with genotype in autosomal dominant cerebellar ataxia type I.Semantic proximity Read ↗

Ocular motor biomarkers in Niemann-Pick disease type C: A prospective cross-sectional multicontinental study in 72 patientsSemantic proximity Read ↗

Upward Gaze Palsy: a Valuable Sign to Distinguish Spinocerebellar Ataxias.Semantic proximity Read ↗

Eye movement alterations in presymptomatic C9orf72 expansion gene carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.