Article
Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites.
Malaria journal - 10 Feb 2017
Mkumbaye Sixbert I, Minja Daniel T R, Jespersen Jakob S, Alifrangis Michael, Kavishe Reginald A, Mwakalinga Steven B, Lusingu John P, Theander Thor G, Lavstsen Thomas, Wang Christian W
Abstract excerpt
BACKGROUND: Establishing in vitro Plasmodium falciparum culture lines from patient parasite isolates can offer deeper understanding of geographic variations of drug sensitivity and mechanisms of malaria pathogenesis and immunity. Cellulose column filtration of blood is an inexpensive, rapid and effective method for the removal of host factors, such as leucocytes and platelets, significantly improving the...
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