Article
Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay
9 Feb 2017
Abstract excerpt
Human papillomaviruses (HPVs) are oncogenic viruses that cause numerous different cancers as well as benign lesions in the epithelia.To date, there is no effective cure for an ongoing HPV infection.Here, we describe the generation process of a platform for the development of anti-HPV drugs.This system consists of engineered full-length HPV genomes that express reporter genes for evaluation of the viral copy...
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