Article
Comparative analysis of microRNA expression profiles between A549, A549/DDP and their respective exosomes.
Oncotarget - 27 Jun 2017
Qin Xiaobing, Yu Shaorong, Xu Xiaoyue, Shen Bo, Feng Jifeng
Abstract excerpt
Exosomes were reported to transport bioactive molecules and influence the biology behavior of recipient cells. In order to study the role of exosomal microRNAs in the mechanism of cisplatin resistance to lung cancer cells, we analyzed the expression profiles of microRNAs in A549, A549/DDP cells and their exosomes by microarray. The results showed that a certain proportion of microRNAs were co-expressed in the...
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