Article
Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation.
The New England journal of medicine - 9 Feb 2017
Lindsley R Coleman, Saber Wael, Mar Brenton G, Redd Robert, Wang Tao, Haagenson Michael D, Grauman Peter V, Hu Zhen-Huan, Spellman Stephen R, Lee Stephanie J, Verneris Michael R, Hsu Katharine, Fleischhauer Katharina, Cutler Corey, Antin Joseph H, Neuberg Donna, Ebert Benjamin L
Abstract excerpt
BACKGROUND: Genetic mutations drive the pathogenesis of the myelodysplastic syndrome (MDS) and are closely associated with clinical phenotype. Therefore, genetic mutations may predict clinical outcomes after allogeneic hematopoietic stem-cell transplantation. METHODS: We performed targeted mutational analysis on samples obtained before transplantation from 1514 patients with MDS who were enrolled in the Center...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.