RNA-Seq Analysis of Gene Expression, Viral Pathogen, and B-Cell/T-Cell Receptor Signatures in Complex Chronic Disease.

doi:10.1093/cid/ciw767

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RNA-Seq Analysis of Gene Expression, Viral Pathogen, and B-Cell/T-Cell Receptor Signatures in Complex Chronic Disease.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2017

Bouquet Jerome, Gardy Jennifer L, Brown Scott, Pfeil Jacob, Miller Ruth R, Morshed Muhammad, Avina-Zubieta Antonio, Shojania Kam, McCabe Mark, Parker Shoshana, Uyaguari Miguel, Federman Scot, Tang Patrick, Steiner Ted, Otterstater Michael, Holt Rob, Moore Richard, Chiu Charles Y, Patrick David M

Abstract excerpt

Background: Chronic fatigue syndrome (CFS) remains poorly understood. Although infections are speculated to trigger the syndrome, a specific infectious agent and underlying pathophysiological mechanism remain elusive. In a previous study, we described similar clinical phenotypes in CFS patients and alternatively diagnosed chronic Lyme syndrome (ADCLS) patients—individuals diagnosed with Lyme disease by testing...

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PMID: 28172519
DOI: 10.1093/cid/ciw767
PMCID: PMC5850034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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