Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temozolomide in the Era of Precision Medicine

4 Feb 2017

Abstract excerpt

Abstract In the January 1, 2017, issue of Cancer Research, Nagel and colleagues demonstrate the value of assays that determine the DNA repair capacity of cancers in predicting response to temozolomide. Using a fluorescence-based multiplex flow cytometric host cell reactivation assay that provides simultaneous readout of DNA repair capacity across multiple pathways, they show that the multivariate drug response...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28159862
DOI: 10.1158/0008-5472.can-16-2983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temozolomide in the Era of Precision MedicinePMID 28159862Read ↗

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma MultiformeSemantic proximity Read ↗

Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere modelsSemantic proximity Read ↗

A multifaceted review of temozolomide resistance mechanisms in glioblastoma beyond O-6-methylguanine-DNA methyltransferaseSemantic proximity Read ↗

Mechanisms of Resistance to Current Glioblastoma TherapiesSemantic proximity Read ↗

Functional Precision Oncology: The Next Frontier to Improve Glioblastoma Outcome?Semantic proximity Read ↗

Recent Approaches to Improve the Antitumor Efficacy of TemozolomideSemantic proximity Read ↗

Genetic and epigenetic landscape of O6-methylguanine-DNA methyltransferase (MGMT): implications for DNA repair and cancer therapeuticsSemantic proximity Read ↗

Mitigating temozolomide resistance in glioblastoma via DNA damage-repair inhibitionSemantic proximity Read ↗

A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the<i>O</i>6-Methylguanine-DNA Methyltransferase PromoterSemantic proximity Read ↗

The Role of Mismatch Repair in Glioblastoma Multiforme Treatment Response and ResistanceSemantic proximity Read ↗

Comprehensive Whole Genome Sequencing Reveals Origins of Mutational Signatures Associated with Aging and Temozolomide ChemotherapySemantic proximity Read ↗

Mitigating Temozolomide Resistance in Glioblastoma via DNA Damage-Repair InhibitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.