Studies of an Androgen-Binding Protein Knockout Corroborate a Role for Salivary ABP in Mouse Communication.

doi:10.1534/genetics.116.194571

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Article

Studies of an Androgen-Binding Protein Knockout Corroborate a Role for Salivary ABP in Mouse Communication.

Genetics - 1 Apr 2017

Chung Amanda G, Belone Phillip M, Bímová Barbora Vošlajerová, Karn Robert C, Laukaitis Christina M

Abstract excerpt

The house mouse Androgen-binding protein (Abp) gene family is comprised of 64 paralogs, 30 Abpa and 34 Abpbg, encoding the alpha (ABPA) and beta-gamma (ABPBG) protein subunits that are disulfide-bridged to form dimers in secretions. Only 14 Abp genes are expressed in distinct patterns in the lacrimal (11) and submandibular glands (3). We created a knockout mouse line lacking two of the three genes expressed in...

Topics

Androgen-Binding Protein
Animals
Female
Fertility
Longevity
Male
Mating Preference, Animal
Maze Learning
Mice
Phenotype
Proteome
Saliva
Salivary Glands

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Identifiers

PMID: 28159752
DOI: 10.1534/genetics.116.194571
PMCID: PMC5378110

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